TY - JOUR
T1 - Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia
AU - Wardenburg, Juliane Bubeck
AU - Patel, Ravi J.
AU - Schneewind, Olaf
PY - 2007/2
Y1 - 2007/2
N2 - A model of Staphylococcus aureus-induced pneumonia in adult, immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and pathological features of pneumonia in human patients. Using this system, we defined a role for S. aureus strain Newman surface proteins and secreted exotoxins in pneumonia-related mortality.
AB - A model of Staphylococcus aureus-induced pneumonia in adult, immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and pathological features of pneumonia in human patients. Using this system, we defined a role for S. aureus strain Newman surface proteins and secreted exotoxins in pneumonia-related mortality.
UR - http://www.scopus.com/inward/record.url?scp=33846814907&partnerID=8YFLogxK
U2 - 10.1128/IAI.01313-06
DO - 10.1128/IAI.01313-06
M3 - Article
C2 - 17101657
AN - SCOPUS:33846814907
SN - 0019-9567
VL - 75
SP - 1040
EP - 1044
JO - Infection and immunity
JF - Infection and immunity
IS - 2
ER -