Surface immunoglobulin and the lymphocyte cytoskeleton

J. Braun, E. R. Unanue

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Surface immunoglobulin, the key surface receptor of B lymphocytes, undergoes ligand-dependent interaction with the cell cytoskeleton. The capacity of this receptor to associate with and activate the contractile apparatus mediates its unique influence on the lymphocyte physiology: membrane reorganization, chemotaxis, and receptor-ligand endocytosis. Features of this receptor-cytoskeleton interaction are probed with a simple but powerful detergent fractionation technique.

Original languageEnglish
Pages (from-to)2446-2451
Number of pages6
JournalFederation proceedings
Volume42
Issue number8
StatePublished - Jan 1 1983
Externally publishedYes

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