Abstract
Surface immunoglobulin, the key surface receptor of B lymphocytes, undergoes ligand-dependent interaction with the cell cytoskeleton. The capacity of this receptor to associate with and activate the contractile apparatus mediates its unique influence on the lymphocyte physiology: membrane reorganization, chemotaxis, and receptor-ligand endocytosis. Features of this receptor-cytoskeleton interaction are probed with a simple but powerful detergent fractionation technique.
| Original language | English |
|---|---|
| Pages (from-to) | 2446-2451 |
| Number of pages | 6 |
| Journal | Federation proceedings |
| Volume | 42 |
| Issue number | 8 |
| State | Published - Jan 1 1983 |