Support of cochlear metabolic and ion transport processes solely by perilymphatic perfusion

D. C. Marcus, T. Kobayashi, M. Rokugo, N. Y. Marcus, I. Thalmann, R. Thalmann

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Morphologic considerations would seem to suggest that the cochlear duct could not be maintained in a fully functional state in the absence of a blood supply. We found, however, that perilymphatic perfusion could be used as a substitute for the normal vascular circulation. The criteria used to determine cochlear function included (1) normal endocochlear potential, (2) normal net secretory flux of rubidium (as a tracer for K), and (3) normal levels of ATP in both the organ of Corti and the stria vascularis. All criteria were satisfied by our perfusion regimen.

Original languageEnglish
Pages (from-to)287-292
Number of pages6
JournalHearing research
Volume15
Issue number3
DOIs
StatePublished - Sep 1984

Keywords

  • cochlear duct
  • guinea pig
  • ion transport

Fingerprint Dive into the research topics of 'Support of cochlear metabolic and ion transport processes solely by perilymphatic perfusion'. Together they form a unique fingerprint.

  • Cite this