Abstract
Morphologic considerations would seem to suggest that the cochlear duct could not be maintained in a fully functional state in the absence of a blood supply. We found, however, that perilymphatic perfusion could be used as a substitute for the normal vascular circulation. The criteria used to determine cochlear function included (1) normal endocochlear potential, (2) normal net secretory flux of rubidium (as a tracer for K), and (3) normal levels of ATP in both the organ of Corti and the stria vascularis. All criteria were satisfied by our perfusion regimen.
Original language | English |
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Pages (from-to) | 287-292 |
Number of pages | 6 |
Journal | Hearing research |
Volume | 15 |
Issue number | 3 |
DOIs | |
State | Published - Sep 1984 |
Keywords
- cochlear duct
- guinea pig
- ion transport