99mTc-pyrophosphate imaging in acute pericarditis: A clinical and experimental study

J. L. Fleg, B. A. Siegel, J. R. Williamson, R. Roberts

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Fifteen patients with clinical and electrocardiographic features of acute pericarditis underwent myocardial scintigraphy using 99mTc-pyrophosphate. All had normal images. In 5 additional patients with acute pericarditis and evidence of ischemic heart disease, 99mTc-pyrophosphate images showed focal abnormalities in 2 patients and equivocal findings in 2. Serial myocardial radionuclide images were obtained 2 to 18 days after induction of pericarditis in 8 dogs; all images were normal. No stainable tissue calcium was demonstrated histochemically in the pericardium or myocardium of these dogs. The results suggest that 99mTc-PYP myocardial radionuclide images are normal in acute pericarditis in the absence of ischemic heart disease.

Original languageEnglish
Pages (from-to)727-731
Number of pages5
Issue number3
StatePublished - Jan 1 1978


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