203Pb-VMT-α-NET Scintigraphy of a Patient with Neuroendocrine Tumor

Dirk Müller; Hendrik Herrmann; Michael K. Schultz; Christoph Solbach; Thomas Ettrich; Vikas Prasad

doi:10.1097/RLU.0000000000004464

²⁰³Pb-VMT-α-NET Scintigraphy of a Patient with Neuroendocrine Tumor

Dirk Müller, Hendrik Herrmann, Michael K. Schultz, Christoph Solbach, Thomas Ettrich, Vikas Prasad

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

In an end-stage midgut neuroendocrine tumor patient with carcinoid heart disease, right ventricular dysfunction, mildly reduced renal function, and refractory to 6 cycles of 177Lu-HA-DOTATATE therapy, planar, and 22 hours SPECT/CT images were acquired after injection of 224 MBq of 203Pb-VMT-α-NET to assess the feasibility of performing 212Pb-VMT-α-NET therapy. A comparison of the 1.5 and 22 hours SPECT/CT images with 68Ga-HA-DOTATATE PET/CT showed high uptake of 203Pb-VMT-α-NET in liver metastases matching with the results of the PET/CT investigation.

Original language	English
Pages (from-to)	54-55
Number of pages	2
Journal	Clinical nuclear medicine
Volume	48
Issue number	1
DOIs	https://doi.org/10.1097/RLU.0000000000004464
State	Published - Jan 1 2023

Keywords

Pb
Pb
SPECT/CT
Tyr3-octreotide
VMT-α-NET

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10.1097/RLU.0000000000004464

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title = "203Pb-VMT-α-NET Scintigraphy of a Patient with Neuroendocrine Tumor",

abstract = "In an end-stage midgut neuroendocrine tumor patient with carcinoid heart disease, right ventricular dysfunction, mildly reduced renal function, and refractory to 6 cycles of 177Lu-HA-DOTATATE therapy, planar, and 22 hours SPECT/CT images were acquired after injection of 224 MBq of 203Pb-VMT-α-NET to assess the feasibility of performing 212Pb-VMT-α-NET therapy. A comparison of the 1.5 and 22 hours SPECT/CT images with 68Ga-HA-DOTATATE PET/CT showed high uptake of 203Pb-VMT-α-NET in liver metastases matching with the results of the PET/CT investigation.",

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AU - Müller, Dirk

AU - Herrmann, Hendrik

AU - Schultz, Michael K.

AU - Solbach, Christoph

AU - Ettrich, Thomas

AU - Prasad, Vikas

PY - 2023/1/1

Y1 - 2023/1/1

N2 - In an end-stage midgut neuroendocrine tumor patient with carcinoid heart disease, right ventricular dysfunction, mildly reduced renal function, and refractory to 6 cycles of 177Lu-HA-DOTATATE therapy, planar, and 22 hours SPECT/CT images were acquired after injection of 224 MBq of 203Pb-VMT-α-NET to assess the feasibility of performing 212Pb-VMT-α-NET therapy. A comparison of the 1.5 and 22 hours SPECT/CT images with 68Ga-HA-DOTATATE PET/CT showed high uptake of 203Pb-VMT-α-NET in liver metastases matching with the results of the PET/CT investigation.

AB - In an end-stage midgut neuroendocrine tumor patient with carcinoid heart disease, right ventricular dysfunction, mildly reduced renal function, and refractory to 6 cycles of 177Lu-HA-DOTATATE therapy, planar, and 22 hours SPECT/CT images were acquired after injection of 224 MBq of 203Pb-VMT-α-NET to assess the feasibility of performing 212Pb-VMT-α-NET therapy. A comparison of the 1.5 and 22 hours SPECT/CT images with 68Ga-HA-DOTATATE PET/CT showed high uptake of 203Pb-VMT-α-NET in liver metastases matching with the results of the PET/CT investigation.

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KW - SPECT/CT

KW - Tyr3-octreotide

KW - VMT-α-NET

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JO - Clinical nuclear medicine

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ER -

²⁰³Pb-VMT-α-NET Scintigraphy of a Patient with Neuroendocrine Tumor

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Keywords

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