[18F]-labeled 3-deoxy-3-fluoro-D-glucose: Synthesis and preliminary biodistribution data

T. J. Tewson, M. J. Welch, M. E. Raichle

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Abstract

A cyclotron target system for the production of anhydrous [18F] fluoride ion has been developed and used for the synthesis of carrier-free [18F]-3 deoxy-3-fluoro-D-glucose (3-FDG). The synthesis is sufficiently rapid and efficient to allow production to usable amounts of 3-FDG with a 6-MeV cyclotron. Preliminary animal studies show that 3-FDG is in fact a glucose analog.

Original languageEnglish
Pages (from-to)1339-1345
Number of pages7
JournalJournal of Nuclear Medicine
Volume19
Issue number12
StatePublished - Jan 1 1978

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