[18F]-labeled 3-deoxy-3-fluoro-D-glucose: Synthesis and preliminary biodistribution data

T. J. Tewson; M. J. Welch; M. E. Raichle

[¹⁸F]-labeled 3-deoxy-3-fluoro-D-glucose: Synthesis and preliminary biodistribution data

T. J. Tewson, M. J. Welch, M. E. Raichle

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Abstract

A cyclotron target system for the production of anhydrous [¹⁸F] fluoride ion has been developed and used for the synthesis of carrier-free [¹⁸F]-3 deoxy-3-fluoro-D-glucose (3-FDG). The synthesis is sufficiently rapid and efficient to allow production to usable amounts of 3-FDG with a 6-MeV cyclotron. Preliminary animal studies show that 3-FDG is in fact a glucose analog.

Original language	English
Pages (from-to)	1339-1345
Number of pages	7
Journal	Journal of Nuclear Medicine
Volume	19
Issue number	12
State	Published - Jan 1 1978

Cite this

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title = "[18F]-labeled 3-deoxy-3-fluoro-D-glucose: Synthesis and preliminary biodistribution data",

abstract = "A cyclotron target system for the production of anhydrous [18F] fluoride ion has been developed and used for the synthesis of carrier-free [18F]-3 deoxy-3-fluoro-D-glucose (3-FDG). The synthesis is sufficiently rapid and efficient to allow production to usable amounts of 3-FDG with a 6-MeV cyclotron. Preliminary animal studies show that 3-FDG is in fact a glucose analog.",

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AU - Welch, M. J.

AU - Raichle, M. E.

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N2 - A cyclotron target system for the production of anhydrous [18F] fluoride ion has been developed and used for the synthesis of carrier-free [18F]-3 deoxy-3-fluoro-D-glucose (3-FDG). The synthesis is sufficiently rapid and efficient to allow production to usable amounts of 3-FDG with a 6-MeV cyclotron. Preliminary animal studies show that 3-FDG is in fact a glucose analog.

AB - A cyclotron target system for the production of anhydrous [18F] fluoride ion has been developed and used for the synthesis of carrier-free [18F]-3 deoxy-3-fluoro-D-glucose (3-FDG). The synthesis is sufficiently rapid and efficient to allow production to usable amounts of 3-FDG with a 6-MeV cyclotron. Preliminary animal studies show that 3-FDG is in fact a glucose analog.

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M3 - Article

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JF - Journal of Nuclear Medicine

IS - 12

ER -

[¹⁸F]-labeled 3-deoxy-3-fluoro-D-glucose: Synthesis and preliminary biodistribution data

Abstract

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