18F-FDG PET/CT in a 16-year-old patient with hydranencephaly

Ryan G. Short, Arash Kardan

Research output: Contribution to journalArticlepeer-review


A 16-year-old male patient with a past medical history of congenital brain malformation presented for surveillance 18F-FDG PET/CT scan of left parotid acinic cell adenocarcinoma. 18F-FDG PET/CT revealed absence of gray matter activity in the bilateral cerebral hemispheres most consistent with hydranencephaly. Hydranencephaly is a rare congenital condition characterized by absent cerebral hemispheres replaced by cerebrospinal fluid-filled sacs. The etiology is hypothesized to be secondary to intrauterine bilateral internal carotid artery compromise. Most affected individuals die in utero or within weeks of birth; however, there are rare reported cases of prolonged survival as in our patient.

Original languageEnglish
Pages (from-to)e445-e447
JournalClinical nuclear medicine
Issue number10
StatePublished - Oct 1 2014


  • Cephalic disorders
  • Hydranencephaly


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