Abstract
Fibrils of the protein α-synuclein (Asyn) are implicated in the pathogenesis of Parkinson Disease, Lewy Body Dementia, and Multiple System Atrophy. Numerous forms of Asyn fibrils have been studied by solid-state NMR and resonance assignments have been reported. Here, we report a new set of 13C, 15N assignments that are unique to fibrils obtained by amplification from postmortem brain tissue of a patient diagnosed with Lewy Body Dementia.
Original language | English |
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Pages (from-to) | 281-286 |
Number of pages | 6 |
Journal | Biomolecular NMR Assignments |
Volume | 17 |
Issue number | 2 |
DOIs | |
State | Published - Dec 2023 |
Keywords
- Fibrils
- Lewy Body Dementia
- Parkinson Disease
- Polymorphism
- αSynuclein