TY - JOUR
T1 - Summary of presentations from the 46th annual meeting of the american society of clinical oncology
T2 - Focus on non-small cell lung cancer (2010)
AU - Stinchcombe, Thomas E.
AU - Baggstrom, Maria Q.
AU - Somaiah, Neeta
AU - Simon, George R.
AU - Govindan, Ramaswamy
PY - 2011/1
Y1 - 2011/1
N2 - The promising results of crizotinib in molecularly selected patients with advanced non-small cell lung cancer (NSCLC) whose tumor cells had a novel fusion protein involving anaplastic lymphoma kinase presented at the 2010 American Society of Clinical Oncology reinforce once again the importance of understanding molecular heterogeneity of lung cancer and careful patient selection. Several other important issues were the subject of presentations related to lung cancer at the recently concluded American Society of Clinical Oncology annual meeting. The articles covered a wide variety of topics including optimal staging techniques to detect mediastinal nodal involvement, the role of platinum-based doublet chemotherapy in the management of elderly patients with advanced NSCLC, use of maintenance therapy with gemcitabine, and the impact of early introduction of organized palliative care in improving the quality of life of patients with advanced NSCLC. This report provides a brief overview of the presentations related to lung cancer that are relevant to clinical practice and future research.
AB - The promising results of crizotinib in molecularly selected patients with advanced non-small cell lung cancer (NSCLC) whose tumor cells had a novel fusion protein involving anaplastic lymphoma kinase presented at the 2010 American Society of Clinical Oncology reinforce once again the importance of understanding molecular heterogeneity of lung cancer and careful patient selection. Several other important issues were the subject of presentations related to lung cancer at the recently concluded American Society of Clinical Oncology annual meeting. The articles covered a wide variety of topics including optimal staging techniques to detect mediastinal nodal involvement, the role of platinum-based doublet chemotherapy in the management of elderly patients with advanced NSCLC, use of maintenance therapy with gemcitabine, and the impact of early introduction of organized palliative care in improving the quality of life of patients with advanced NSCLC. This report provides a brief overview of the presentations related to lung cancer that are relevant to clinical practice and future research.
KW - Crizotinib
KW - Locally advanced non-small cell lung cancer
KW - Maintenance chemotherapy
KW - Palliative care
KW - Superior sulcus tumors
UR - http://www.scopus.com/inward/record.url?scp=78651083956&partnerID=8YFLogxK
U2 - 10.1097/JTO.0b013e3181fd789d
DO - 10.1097/JTO.0b013e3181fd789d
M3 - Article
C2 - 21178721
AN - SCOPUS:78651083956
SN - 1556-0864
VL - 6
SP - 227
EP - 232
JO - Journal of Thoracic Oncology
JF - Journal of Thoracic Oncology
IS - 1
ER -