SugarBind database (SugarBindDB): A resource of pathogen lectins and corresponding glycan targets

Baddr Shakhsheer, Mark Anderson, Khaled Khatib, Leelapavan Tadoori, Lokesh Joshi, Frederique Lisacek, Lynette Hirschman, Elaine Mullen

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

SugarBindDB lists pathogen and biotoxin lectins and their carbohydrate ligands in a searchable format. Information is collected from articles published in peer-reviewed scientific journals. Help files guide the user through the search process and provide a review of structures and names of sugars that appear in human oligosaccharides. Glycans are written in the condensed form of the carbohydrate nomenclature system developed by the International Union of Pure and Applied Chemistry (IUPAC). Since its online publication by The MITRE Corporation in 2005, the database has served as a resource for research on the glycobiology of infectious disease. SugarBindDB is currently hosted by the Swiss Institute of Bioinformatics on the ExPASy server and will be enhanced and linked to related resources as part of the wider UniCarbKB initiative. Enhancements will include the option to display glycans in a variety of formats, including modified 2D condensed IUPAC and symbolic nomenclature.

Original languageEnglish
Pages (from-to)426-431
Number of pages6
JournalJournal of Molecular Recognition
Volume26
Issue number9
DOIs
StatePublished - Sep 2013

Keywords

  • Adhesin
  • database
  • glycan
  • hemagglutinin
  • infection
  • lectin
  • oligosaccharide
  • pathogen

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