Suckling behavior of the infant rat: Modulaton by a developing neurotransmitter system

B. Nock, C. L. Williams, W. G. Hall

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Drugs which alter serotonin receptor activity modified the suckling behavior of 20-day-old rat pups. Suckling could be reinstated in nondeprived pups, which normally do not suckle, by blockade of serotonin receptors with methysergide. Stimulation of serotonin receptors with quipazine inhibited suckling in deprived pups, and this effect was prevented by methysergide pretreatment. This evidence suggests that suckling in weaning age pups is controlled by a serotonergic inhibitory mechanism.

Original languageEnglish
Pages (from-to)277-280
Number of pages4
JournalPharmacology, Biochemistry and Behavior
Volume8
Issue number3
DOIs
StatePublished - Mar 1978

Keywords

  • Development
  • Methysergide
  • Quipazine
  • Serotonin
  • Suckling behavior

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