Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection

Sheenu Sheela, Sawa Ito, Jeffrey R. Strich, Maura Manion, Celina Montemayor-Garcia, Hao Wei Wang, Karolyn A. Oetjen, Kamile A. West, Austin J. Barrett, Mark Parta, Juan Gea-Banacloche, Steven M. Holland, Christopher S. Hourigan, Catherine Lai

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Disseminated Fusarium infection is associated with high mortality in immunocompromised patients. Patients with acute myeloid leukemia (AML) often have an extended duration of neutropenia during intensive induction chemotherapy, consolidation chemotherapy, and hematopoietic stem cell transplantation (SCT). There is no consensus regarding management of invasive disseminated Fusarium infections in the setting of prolonged neutropenia (Tortorano et al., 2014) [1]. We report a case of disseminated Fusarium in a patient with relapsed AML who underwent successful chemotherapy and haplo-identical allogeneic SCT with administration of granulocyte colony stimulating factor (G-CSF) and granulocyte infusions.

Original languageEnglish
Pages (from-to)4-6
Number of pages3
JournalLeukemia Research Reports
Volume8
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Keywords

  • Acute myeloid leukemia
  • Allogenic transplant
  • Fusarium solani

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