Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection

Sheenu Sheela; Sawa Ito; Jeffrey R. Strich; Maura Manion; Celina Montemayor-Garcia; Hao Wei Wang; Karolyn A. Oetjen; Kamile A. West; Austin J. Barrett; Mark Parta; Juan Gea-Banacloche; Steven M. Holland; Christopher S. Hourigan; Catherine Lai

doi:10.1016/j.lrr.2017.07.001

Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection

Sheenu Sheela, Sawa Ito, Jeffrey R. Strich, Maura Manion, Celina Montemayor-Garcia, Hao Wei Wang, Karolyn A. Oetjen, Kamile A. West, Austin J. Barrett, Mark Parta, Juan Gea-Banacloche, Steven M. Holland, Christopher S. Hourigan, Catherine Lai

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Disseminated Fusarium infection is associated with high mortality in immunocompromised patients. Patients with acute myeloid leukemia (AML) often have an extended duration of neutropenia during intensive induction chemotherapy, consolidation chemotherapy, and hematopoietic stem cell transplantation (SCT). There is no consensus regarding management of invasive disseminated Fusarium infections in the setting of prolonged neutropenia (Tortorano et al., 2014) [1]. We report a case of disseminated Fusarium in a patient with relapsed AML who underwent successful chemotherapy and haplo-identical allogeneic SCT with administration of granulocyte colony stimulating factor (G-CSF) and granulocyte infusions.

Original language	English
Pages (from-to)	4-6
Number of pages	3
Journal	Leukemia Research Reports
Volume	8
DOIs	https://doi.org/10.1016/j.lrr.2017.07.001
State	Published - 2017

Keywords

Acute myeloid leukemia
Allogenic transplant
Fusarium solani

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10.1016/j.lrr.2017.07.001

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Sheela, S., Ito, S., Strich, J. R., Manion, M., Montemayor-Garcia, C., Wang, H. W., Oetjen, K. A., West, K. A., Barrett, A. J., Parta, M., Gea-Banacloche, J., Holland, S. M., Hourigan, C. S., & Lai, C. (2017). Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection. Leukemia Research Reports, 8, 4-6. https://doi.org/10.1016/j.lrr.2017.07.001

@article{324e71eb52814b189c6d78165278cb9a,

title = "Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection",

abstract = "Disseminated Fusarium infection is associated with high mortality in immunocompromised patients. Patients with acute myeloid leukemia (AML) often have an extended duration of neutropenia during intensive induction chemotherapy, consolidation chemotherapy, and hematopoietic stem cell transplantation (SCT). There is no consensus regarding management of invasive disseminated Fusarium infections in the setting of prolonged neutropenia (Tortorano et al., 2014) [1]. We report a case of disseminated Fusarium in a patient with relapsed AML who underwent successful chemotherapy and haplo-identical allogeneic SCT with administration of granulocyte colony stimulating factor (G-CSF) and granulocyte infusions.",

keywords = "Acute myeloid leukemia, Allogenic transplant, Fusarium solani",

author = "Sheenu Sheela and Sawa Ito and Strich, {Jeffrey R.} and Maura Manion and Celina Montemayor-Garcia and Wang, {Hao Wei} and Oetjen, {Karolyn A.} and West, {Kamile A.} and Barrett, {Austin J.} and Mark Parta and Juan Gea-Banacloche and Holland, {Steven M.} and Hourigan, {Christopher S.} and Catherine Lai",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2017",

doi = "10.1016/j.lrr.2017.07.001",

language = "English",

volume = "8",

pages = "4--6",

journal = "Leukemia Research Reports",

issn = "2213-0489",

}

Sheela, S, Ito, S, Strich, JR, Manion, M, Montemayor-Garcia, C, Wang, HW, Oetjen, KA, West, KA, Barrett, AJ, Parta, M, Gea-Banacloche, J, Holland, SM, Hourigan, CS & Lai, C 2017, 'Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection', Leukemia Research Reports, vol. 8, pp. 4-6. https://doi.org/10.1016/j.lrr.2017.07.001

TY - JOUR

T1 - Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection

AU - Sheela, Sheenu

AU - Ito, Sawa

AU - Strich, Jeffrey R.

AU - Manion, Maura

AU - Montemayor-Garcia, Celina

AU - Wang, Hao Wei

AU - Oetjen, Karolyn A.

AU - West, Kamile A.

AU - Barrett, Austin J.

AU - Parta, Mark

AU - Gea-Banacloche, Juan

AU - Holland, Steven M.

AU - Hourigan, Christopher S.

AU - Lai, Catherine

PY - 2017

Y1 - 2017

N2 - Disseminated Fusarium infection is associated with high mortality in immunocompromised patients. Patients with acute myeloid leukemia (AML) often have an extended duration of neutropenia during intensive induction chemotherapy, consolidation chemotherapy, and hematopoietic stem cell transplantation (SCT). There is no consensus regarding management of invasive disseminated Fusarium infections in the setting of prolonged neutropenia (Tortorano et al., 2014) [1]. We report a case of disseminated Fusarium in a patient with relapsed AML who underwent successful chemotherapy and haplo-identical allogeneic SCT with administration of granulocyte colony stimulating factor (G-CSF) and granulocyte infusions.

AB - Disseminated Fusarium infection is associated with high mortality in immunocompromised patients. Patients with acute myeloid leukemia (AML) often have an extended duration of neutropenia during intensive induction chemotherapy, consolidation chemotherapy, and hematopoietic stem cell transplantation (SCT). There is no consensus regarding management of invasive disseminated Fusarium infections in the setting of prolonged neutropenia (Tortorano et al., 2014) [1]. We report a case of disseminated Fusarium in a patient with relapsed AML who underwent successful chemotherapy and haplo-identical allogeneic SCT with administration of granulocyte colony stimulating factor (G-CSF) and granulocyte infusions.

KW - Acute myeloid leukemia

KW - Allogenic transplant

KW - Fusarium solani

UR - http://www.scopus.com/inward/record.url?scp=85025679435&partnerID=8YFLogxK

U2 - 10.1016/j.lrr.2017.07.001

DO - 10.1016/j.lrr.2017.07.001

M3 - Article

C2 - 28794968

AN - SCOPUS:85025679435

SN - 2213-0489

VL - 8

SP - 4

EP - 6

JO - Leukemia Research Reports

JF - Leukemia Research Reports

ER -

Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection

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