Successful resection after neoadjuvant therapy in pancreatic adenocarcinoma

Parvin F. Peddi, Andrea Wang-Gillam

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A 59-year-old woman presented with borderline resectable pancreatic adenocarcinoma involving the neck and body of the pancreas. She was treated with systemic chemotherapy followed by chemoradiation, with subsequent downstaging of the tumor by imaging. Subsequent resection had negative margins and negative lymph nodes with only microscopic disease present in the tumor specimen. Neoadjuvant therapy is controversial but could play a role in borderline resectable disease by allowing for higher chance of negative margins at surgery and increasing the chance for cure in these patients. Microscopic disease at time of resection is rare.

Original languageEnglish
Pages (from-to)1330-1334
Number of pages5
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number11
StatePublished - Nov 1 2012


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