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Subunit-specific action of an anticonvulsant thiobutyrolactone on recombinant glycine receptors involves a residue in the M2 membrane-spanning region
Joe Henry Steinbach
, John Bracamontes
, Li Yu
, Pengnian Zhang
,
Douglas F. Covey
Department of Developmental Biology
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Neurosciences
Research output
:
Contribution to journal
›
Article
›
peer-review
25
Scopus citations
Overview
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Keyphrases
Recombinant
100%
Methyl
100%
Anticonvulsant
100%
Ethyl
100%
Glycine Receptor
100%
Specific Action
100%
Glycine
75%
Picrotin
62%
Potentiation
25%
Picrotoxin
25%
Co-expression
12%
High Concentration
12%
Overlapping Sets
12%
Adult Brain
12%
Receptor Subunits
12%
Allosteric Mechanism
12%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Anticonvulsive Agent
100%
Glycine Receptor
100%
Picrotoxinin
33%
Alanine
16%
Receptor Subunit
16%
Neuroscience
Glycine Receptor
100%
Receptor
100%
Anticonvulsant
100%
Receptor Subunit
16%
Alanine
16%