Substitution effect on the regioselective halogen/metal exchange of 3-substituted 1,2,5-tribromobenzenes

Karsten Menzel; Paul M. Mills; Doug E. Frantz; Todd D. Nelson; Michael H. Kress

doi:10.1016/j.tetlet.2007.11.124

Substitution effect on the regioselective halogen/metal exchange of 3-substituted 1,2,5-tribromobenzenes

Karsten Menzel
, Paul M. Mills
, Doug E. Frantz
, Todd D. Nelson
, Michael H. Kress

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Regioselective halogen/metal exchange reactions using isopropylmagnesium chloride were studied on 3-substituted 1,2,5-tribromoarenes. Seven examples are given.

Original language	English
Pages (from-to)	415-418
Number of pages	4
Journal	Tetrahedron Letters
Volume	49
Issue number	3
DOIs	https://doi.org/10.1016/j.tetlet.2007.11.124
State	Published - Jan 14 2008

Keywords

1,2-Dibromobenzene
Carboxylic acids
Grignard reactions
Halogen/metal exchange
Regioselectivity

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10.1016/j.tetlet.2007.11.124

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title = "Substitution effect on the regioselective halogen/metal exchange of 3-substituted 1,2,5-tribromobenzenes",

abstract = "Regioselective halogen/metal exchange reactions using isopropylmagnesium chloride were studied on 3-substituted 1,2,5-tribromoarenes. Seven examples are given.",

keywords = "1,2-Dibromobenzene, Carboxylic acids, Grignard reactions, Halogen/metal exchange, Regioselectivity",

author = "Karsten Menzel and Mills, \{Paul M.\} and Frantz, \{Doug E.\} and Nelson, \{Todd D.\} and Kress, \{Michael H.\}",

year = "2008",

month = jan,

day = "14",

doi = "10.1016/j.tetlet.2007.11.124",

language = "English",

volume = "49",

pages = "415--418",

journal = "Tetrahedron Letters",

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T1 - Substitution effect on the regioselective halogen/metal exchange of 3-substituted 1,2,5-tribromobenzenes

AU - Menzel, Karsten

AU - Mills, Paul M.

AU - Frantz, Doug E.

AU - Nelson, Todd D.

AU - Kress, Michael H.

PY - 2008/1/14

Y1 - 2008/1/14

N2 - Regioselective halogen/metal exchange reactions using isopropylmagnesium chloride were studied on 3-substituted 1,2,5-tribromoarenes. Seven examples are given.

AB - Regioselective halogen/metal exchange reactions using isopropylmagnesium chloride were studied on 3-substituted 1,2,5-tribromoarenes. Seven examples are given.

KW - 1,2-Dibromobenzene

KW - Carboxylic acids

KW - Grignard reactions

KW - Halogen/metal exchange

KW - Regioselectivity

UR - https://www.scopus.com/pages/publications/37449011577

U2 - 10.1016/j.tetlet.2007.11.124

DO - 10.1016/j.tetlet.2007.11.124

M3 - Article

AN - SCOPUS:37449011577

SN - 0040-4039

VL - 49

SP - 415

EP - 418

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 3

ER -

Substitution effect on the regioselective halogen/metal exchange of 3-substituted 1,2,5-tribromobenzenes

Abstract

Keywords

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