Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration

Keyphrases

• Adaptation 33%
• Cell Behavior 66%
• Cell Migration 100%
• Chemoattractant 33%
• Direct Control 33%
• Directed Cell Migration 33%
• Directional Sensing 33%
• Extracellular Cues 33%
• G Protein 100%
• G Protein Signaling 33%
• G Protein Subunit 33%
• G Protein-coupled Receptor 66%
• Gi Signaling 33%
• Global Inhibition 33%
• Immune Cells 33%
• Inhibition Pathway 33%
• Intracellular Signaling Molecules 33%
• Light-triggered 33%
• Living Cells 33%
• Neurite Initiation 33%
• Optogenetic Stimulation 100%
• Optogenetic Tools 100%
• Plasma Membrane 33%
• Polarized Cells 33%
• Regulator of G Protein Signaling 33%
• Selected Region 33%
• Sequester 33%
• Signaling Activity 33%
• Signaling Gradient 100%
• Signaling Molecules 33%
• Spatial Control 33%
• Static Information 33%
• Temporal Control 33%

Biochemistry, Genetics and Molecular Biology

• Cell Function 50%
• Cell Membrane 25%
• Cell Migration 100%
• G Protein 100%
• G Protein Coupled Receptor 50%
• Heterotrimeric G Protein 25%
• Immunocompetent Cell 25%
• Intracellular Signaling 25%
• Optogenetics 100%
• Protein Subunit 50%
• Regulator of G Protein Signalling 25%
• Signaling Protein 25%
• Synapsin I 25%