TY - JOUR
T1 - Studying brain organization via spontaneous fMRI signal
AU - Power, Jonathan D.
AU - Schlaggar, Bradley L.
AU - Petersen, Steven E.
N1 - Publisher Copyright:
© 2014 Elsevier Inc.
PY - 2014/11/19
Y1 - 2014/11/19
N2 - In recent years, some substantial advances in understanding human (and nonhuman) brain organization have emerged from a relatively unusual approach: the observation of spontaneous activity, and correlated patterns in spontaneous activity, in the "resting" brain. Most commonly, spontaneous neural activity is measured indirectly via fMRI signal in subjects who are lying quietly in the scanner, the so-called "resting state." This Primer introduces the fMRI-based study of spontaneous brain activity, some of the methodological issues active in the field, and some ways in which resting-state fMRI has been used to delineate aspects of area-level and supra-areal brain organization. Human brain organization, in health and disease, is increasingly studied by measuring spontaneous brain activity with fMRI. This Primer explains how researchers study these fMRI signals, and what these signals might reveal about brain organization.
AB - In recent years, some substantial advances in understanding human (and nonhuman) brain organization have emerged from a relatively unusual approach: the observation of spontaneous activity, and correlated patterns in spontaneous activity, in the "resting" brain. Most commonly, spontaneous neural activity is measured indirectly via fMRI signal in subjects who are lying quietly in the scanner, the so-called "resting state." This Primer introduces the fMRI-based study of spontaneous brain activity, some of the methodological issues active in the field, and some ways in which resting-state fMRI has been used to delineate aspects of area-level and supra-areal brain organization. Human brain organization, in health and disease, is increasingly studied by measuring spontaneous brain activity with fMRI. This Primer explains how researchers study these fMRI signals, and what these signals might reveal about brain organization.
UR - http://www.scopus.com/inward/record.url?scp=84918820437&partnerID=8YFLogxK
U2 - 10.1016/j.neuron.2014.09.007
DO - 10.1016/j.neuron.2014.09.007
M3 - Review article
C2 - 25459408
AN - SCOPUS:84918820437
SN - 0896-6273
VL - 84
SP - 681
EP - 696
JO - Neuron
JF - Neuron
IS - 4
ER -