Abstract
The study of covalent binding between estrogen quinones (EQ) and oligonucleotides by electrospray mass spectrometry (MS) is discussed. The resulting adducts may be implicated in human breast cancer. 2,3-EQ plays an important role by bonding covalently with DNA to give stable adducts. It is found that the 2,3-EQ forms a stable adduct that can be detected by matrix assisted laser desorption ionization/time of flight (MALDI/TOF) MS.
Original language | English |
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Pages | 433-434 |
Number of pages | 2 |
State | Published - 2002 |
Event | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002 |
Conference
Conference | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
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Country/Territory | United States |
City | Orlando, FL |
Period | 06/2/02 → 06/6/02 |