Studies on myofibrillar protein synthesis in chicken muscular dystrophy

Jeremiah J. Morrissey; S. S. Kerwar

doi:10.1016/0024-3205(77)90297-1

Studies on myofibrillar protein synthesis in chicken muscular dystrophy

Jeremiah J. Morrissey, S. S. Kerwar

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3 Scopus citations

Abstract

Myofibrillar proteins synthesized in vitro by normal and dystrophic chicken muscle polysomes were purified and analyzed by SDS gel electrophoresis. No substantial difference in the synthesis of myofibrillar proteins could be detected. These observations suggest that the loss of muscle mass that is observed in muscular dystrophy is not related to a translational defect in the dystrophic polysomes.

Original language	English
Pages (from-to)	1091-1095
Number of pages	5
Journal	Life Sciences
Volume	20
Issue number	6
DOIs	https://doi.org/10.1016/0024-3205(77)90297-1
State	Published - Mar 15 1977

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title = "Studies on myofibrillar protein synthesis in chicken muscular dystrophy",

abstract = "Myofibrillar proteins synthesized in vitro by normal and dystrophic chicken muscle polysomes were purified and analyzed by SDS gel electrophoresis. No substantial difference in the synthesis of myofibrillar proteins could be detected. These observations suggest that the loss of muscle mass that is observed in muscular dystrophy is not related to a translational defect in the dystrophic polysomes.",

author = "Morrissey, {Jeremiah J.} and Kerwar, {S. S.}",

year = "1977",

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T1 - Studies on myofibrillar protein synthesis in chicken muscular dystrophy

AU - Morrissey, Jeremiah J.

AU - Kerwar, S. S.

PY - 1977/3/15

Y1 - 1977/3/15

N2 - Myofibrillar proteins synthesized in vitro by normal and dystrophic chicken muscle polysomes were purified and analyzed by SDS gel electrophoresis. No substantial difference in the synthesis of myofibrillar proteins could be detected. These observations suggest that the loss of muscle mass that is observed in muscular dystrophy is not related to a translational defect in the dystrophic polysomes.

AB - Myofibrillar proteins synthesized in vitro by normal and dystrophic chicken muscle polysomes were purified and analyzed by SDS gel electrophoresis. No substantial difference in the synthesis of myofibrillar proteins could be detected. These observations suggest that the loss of muscle mass that is observed in muscular dystrophy is not related to a translational defect in the dystrophic polysomes.

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U2 - 10.1016/0024-3205(77)90297-1

DO - 10.1016/0024-3205(77)90297-1

M3 - Article

C2 - 850460

AN - SCOPUS:0017397863

SN - 0024-3205

VL - 20

SP - 1091

EP - 1095

JO - Life Sciences

JF - Life Sciences

IS - 6

ER -

Studies on myofibrillar protein synthesis in chicken muscular dystrophy

Abstract

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