TY - JOUR
T1 - Structure of the DNA binding domain of E. coli SSB bound to ssDNA
AU - Raghunathan, Srinivasan
AU - Kozlov, Alexander G.
AU - Lohman, Timothy M.
AU - Waksman, Gabriel
N1 - Funding Information:
G.W. and T.M.L were supported in this work by the NIH. We gratefully acknowledge T. Ho for synthesis and purification of oligodeoxynucleotides, S. Korolev and K. Fütterer for help during data collection, and the staff of beamline BL9.1 of SSRL, beamline X4A of NSLS, and beamline 19ID of APS.
PY - 2000/8
Y1 - 2000/8
N2 - The structure of the homotetrameric DNA binding domain of the single stranded DNA binding protein from Escherichia coil (Eco SSB) bound to two 35-mer single stranded DNAs was determined to a resolution of 2.8 Å. This structure describes the vast network of interactions that results in the extensive wrapping of single stranded DNA around the SSB tetramer and suggests a structural basis for its various binding modes.
AB - The structure of the homotetrameric DNA binding domain of the single stranded DNA binding protein from Escherichia coil (Eco SSB) bound to two 35-mer single stranded DNAs was determined to a resolution of 2.8 Å. This structure describes the vast network of interactions that results in the extensive wrapping of single stranded DNA around the SSB tetramer and suggests a structural basis for its various binding modes.
UR - http://www.scopus.com/inward/record.url?scp=0033887437&partnerID=8YFLogxK
U2 - 10.1038/77943
DO - 10.1038/77943
M3 - Article
C2 - 10932248
AN - SCOPUS:0033887437
VL - 7
SP - 648
EP - 652
JO - Nature Structural Biology
JF - Nature Structural Biology
SN - 1072-8368
IS - 8
ER -