Structure of the complement factor 5a receptor-ligand complex studied by disulfide trapping and molecular modeling

Keyphrases

• Molecular Modeling 100%
• Ligand-receptor Binding 100%
• Ligand Complexes 100%
• Complement Component 5 100%
• Disulfide Trapping 100%
• Cysteine 60%
• Random mutagenesis 60%
• C5aR 40%
• G Protein-coupled Receptor 20%
• N-terminus 20%
• C-terminal Tail 20%
• Novel Technique 20%
• Functional Interaction 20%
• Three Dimensional Model 20%
• Dynamic Equilibrium 20%
• Extracellular Loop 20%
• Intermolecular Interactions 20%
• Receptor Conformation 20%
• Relative Orientation 20%
• Ligand-receptor Pairs 20%
• Single Position 20%
• Anaphylatoxins 20%
• Unpaired Cysteine 20%

Biochemistry, Genetics and Molecular Biology

• Disulfide 100%
• Molecular Model 100%
• Cysteine 100%
• Mutagenesis 75%
• C-Terminus 25%
• G Protein Coupled Receptor 25%
• N-Terminus 25%
• Conformation 25%
• Anaphylatoxin 25%

Immunology and Microbiology

• Molecular Model 100%
• Complement Factor 100%
• Cysteine 80%
• Mutagenesis 60%
• Carboxy Terminal Sequence 20%
• Amino Terminal Sequence 20%
• Conformation 20%
• Intermolecular Interaction 20%
• Anaphylatoxin 20%