Structural insights into RNA recognition and activation of RIG-I-like receptors

Keyphrases

• Antiviral Activity 33%
• ATP Hydrolysis 33%
• ATP Release 33%
• CARD Domain 33%
• Cis-element 33%
• Control Signal 33%
• Double-stranded RNA 33%
• Helicase 33%
• Host Cell 33%
• Innate Immune Pathways 33%
• Melanoma Differentiation-associated Gene 5 (MDA5) 33%
• Multiple Contacts 33%
• Non-self 33%
• Regulatory Mechanism 33%
• Regulatory Process 33%
• Retinoic Acid-inducible Gene I (RIG-I) 33%
• RIG-I-like Receptors 100%
• RNA Activation (RNAa) 100%
• RNA Binding 33%
• RNA Recognition 100%
• RNA-binding Domain 33%
• Signaling Modules 33%
• Signaling Network 33%
• Structural Insights 100%
• Viral Infection 33%
• Viral Pathogenesis 33%

Biochemistry, Genetics and Molecular Biology

• Adenosine Triphosphate 33%
• C-Terminus 33%
• CARD Domain 33%
• Conformation 33%
• Double-Stranded RNA 33%
• Enzymatic Hydrolysis 33%
• Helicase 33%
• Infectious Agent 33%
• MDA5 33%
• Potential Difference 33%
• RIG-I 33%
• RIG-I-like Receptor 100%
• RNA 100%
• RNA Binding 33%
• RNA Recognition Motif 33%

Immunology and Microbiology

• Carboxy Terminal Sequence 33%
• Caspase Activation and Recruitment Domain 33%
• Conformation 33%
• Host Cell 33%
• Infectious Agent 33%
• MDA5 33%
• Potential Difference 33%
• RIG-I 33%
• RIG-I-like Receptor 100%
• RNA Binding 33%
• RNA Recognition Motif 33%
• Viral Disease 33%
• Viral Pathogenesis 33%