Abstract

The structural gene for membrane cofactor protein (MCP), a widely distributed C3b/C4b binding regulatory glycoprotein of the complement system, has been mapped to the same locus as the structural genes for CR1, CR2, DAF, and C4bp. The order of the genes within an ~800-kb DNA fragment on the long arm of chromosome 1 is MCP-CR1-CR2-DAF-C4bp. Further, the MCP gene maps to within 100 kb of 3' end of the CR1 gene.

Original languageEnglish
Pages (from-to)597-602
Number of pages6
JournalJournal of Experimental Medicine
Volume169
Issue number2
DOIs
StatePublished - 1989

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