Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

Keyphrases

• Structural Insights 100%
• Mechanistic Insight 100%
• Transcription Complex 100%
• Cooperative Assembly 100%
• Transcription Factor 50%
• Cooperativity 50%
• X-ray Structure 50%
• Dimerization 50%
• Spacer Length 50%
• Transcriptional Activation 50%
• Two-site 50%
• Recognition Site 50%
• Proteolysis 50%
• Complex Forms 50%
• Hes1 50%
• Notch Signaling 50%
• DNA Bending 50%
• Notch1 50%
• Coactivator 50%
• Organizational Features 50%
• Ankyrin Repeat 50%
• Effector Domain 50%
• Mastermind 50%
• Hes5 50%
• Untwisting 50%
• Activation Complex 50%
• Higher-order Assembly 50%
• Intracellular Effectors 50%
• Feature Control 50%

Biochemistry, Genetics and Molecular Biology

• Promoter Region 100%
• Transcription 100%
• Notch 100%
• Transcription Factors 25%
• Cooperation 25%
• X Ray 25%
• Dimerization 25%
• Transcription Initiation 25%
• Transactivation 25%
• Notch Signaling Pathway 25%
• DNA Bending 25%
• Ankyrin 25%
• HES1 25%
• Proteolysis 25%