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Abstract

Direct and indirect pathway striatal neurons are known to exert opposing control over motor output. In this review, we discuss a hypothetical extension of this framework, in which direct pathway striatal neurons also mediate reinforcement and reward, and indirect pathway neurons mediate punishment and aversion.

Original languageEnglish
Pages (from-to)167-177
Number of pages11
JournalPhysiology
Volume27
Issue number3
DOIs
StatePublished - Jun 1 2012

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