Stress-strain environment around a chondrocyte. A finite element analysis of cell-matrix interactions

F. Guilak, A. Ratcliffe, V. C. Mow

Research output: Contribution to conferencePaper

5 Scopus citations

Abstract

The biosynthetic response of the chondrocyte is dependent on the mechanical environment of the cell. In this paper, we examine mechanical interactions between the chondrocyte and the surrounding extracellular matrix using a linear biphasic finite element model. Results show that the mechanical environment in the immediate vicinity of the cell is highly dependent on the relative differences between the material properties of the cell and the matrix.

Original languageEnglish
Pages395-398
Number of pages4
StatePublished - Dec 1 1990
Externally publishedYes
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Dallas, TX, USA
Duration: Nov 25 1990Nov 30 1990

Conference

ConferenceWinter Annual Meeting of the American Society of Mechanical Engineers
CityDallas, TX, USA
Period11/25/9011/30/90

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    Guilak, F., Ratcliffe, A., & Mow, V. C. (1990). Stress-strain environment around a chondrocyte. A finite element analysis of cell-matrix interactions. 395-398. Paper presented at Winter Annual Meeting of the American Society of Mechanical Engineers, Dallas, TX, USA, .