@article{16dc89d750884c25ae01a5ecb4f8419d,
title = "Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine8-AII",
abstract = "The angiotensin induced release of prostaglandin E (PGE) like material from the isolated perfused rabbit spleen was studied. The PG releasing potency of angiotensin I (AI) was found to be 2-4 % that of angiotensin II (AII). The PG release by AI was shown not to be due to the conversion of AI to AII, but rather to the direct effect of AI. Both AI and AII induced PG release were found to be inhibited by cysteine8-AII. The PG release by epinephrine was not blocked by the angiotensin antagonist. Indomethacin (an inhibitor of PG biosynthesis) blocked the PG release induced by angiotensin or epinephrine.",
author = "Douglas, {James R.} and Johnson, {Eugene M.} and Marshall, {Garland R.} and Jaffe, {Bernard M.} and Philip Needleman",
note = "Funding Information: A knowledgements: This research was su ported by USPHS NIH G&nts HE-14397-02, HE-14509-02, A 1046t6, AM-13025, GM-OOOg6-5-Tog, GM 02016 (Medical Scientist Training Program for J.R.D.) and American Heart Grant 70-672. The authors would like to acknowledge Established Investigatorships of the American Heart Association (PN 68-115 and GRM, 70-111) and a Missouri Heart Fellowship (E.M.J.). The authorsawish to acknowledge the advice of Dr. Mary Ann Marrazzi.",
year = "1973",
month = jan,
doi = "10.1016/0090-6980(73)90138-X",
language = "English",
volume = "3",
pages = "67--74",
journal = "Prostaglandins",
issn = "0090-6980",
number = "1",
}