Sticky platelet syndrome and anterior ischaemic optic neuropathy

Sandeep Randhawa, Gregory P. Van Stavern

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


We report a young patient who presented with nonarteritic anterior ischaemic optic neuropathy associated with the sticky platelet syndrome (SPS, a congenital prothrombotic disorder). A 15-year-old boy presented with a sudden, painless onset of a right inferior altitudinal visual field defect and marked optic disc oedema. Cranial magnetic resonance imaging (including orbits), orbital ultrasound and haematological investigations including a routine hypercoagulability work-up were negative. Further evaluation showed a positive assay for SPS which was confirmed on repeat testing. The SPS (characterized by platelet hyperaggregability and vascular occlusion) may be a potential thrombophilic risk factor for nonarteritic anterior ischaemic optic neuropathy.

Original languageEnglish
Pages (from-to)779-781
Number of pages3
JournalClinical and Experimental Ophthalmology
Issue number8
StatePublished - Nov 2007


  • Hypercoagul ability
  • Optic neuropathy
  • Opticdisc oedema
  • Platelet
  • Thrombosis


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