TY - JOUR
T1 - Steroid Therapy of Brain Edema
T2 - Ineffectiveness in Experimental Cerebral Microembolism
AU - Siegel, Barry A.
AU - Studer, Rebecca K.
AU - Potchen, E. James
PY - 1972/9
Y1 - 1972/9
N2 - Ischemic brain injury was produced in rats by the intracarotid injection of microspheres. During a 72-hour period of study, large doses of dexamethasone did not favorably affect survival, severity of brain edema, brain electrolyte shifts, or alterations in cerebral red blood cell, albumin, and pertechnetate spaces. The role of steroid therapy in cerebral infarction requires critical clinical appraisal.
AB - Ischemic brain injury was produced in rats by the intracarotid injection of microspheres. During a 72-hour period of study, large doses of dexamethasone did not favorably affect survival, severity of brain edema, brain electrolyte shifts, or alterations in cerebral red blood cell, albumin, and pertechnetate spaces. The role of steroid therapy in cerebral infarction requires critical clinical appraisal.
UR - http://www.scopus.com/inward/record.url?scp=0015402477&partnerID=8YFLogxK
U2 - 10.1001/archneur.1972.00490150017004
DO - 10.1001/archneur.1972.00490150017004
M3 - Article
C2 - 5050897
AN - SCOPUS:0015402477
SN - 0003-9942
VL - 27
SP - 209
EP - 212
JO - Archives of Neurology
JF - Archives of Neurology
IS - 3
ER -