Steroid Therapy of Brain Edema: Ineffectiveness in Experimental Cerebral Microembolism

Barry A. Siegel, Rebecca K. Studer, E. James Potchen

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Ischemic brain injury was produced in rats by the intracarotid injection of microspheres. During a 72-hour period of study, large doses of dexamethasone did not favorably affect survival, severity of brain edema, brain electrolyte shifts, or alterations in cerebral red blood cell, albumin, and pertechnetate spaces. The role of steroid therapy in cerebral infarction requires critical clinical appraisal.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalArchives of neurology
Volume27
Issue number3
DOIs
StatePublished - Sep 1972

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