TY - JOUR
T1 - Stereotactic Radiation for Lung Cancer
T2 - A Practical Approach to Challenging Scenarios
AU - Advanced Radiation Therapy Committee for the International Association for the Study of Lung Cancer
AU - Andruska, Neal
AU - Stowe, Hayley B.
AU - Crockett, Cathryn
AU - Liu, Wei
AU - Palma, David
AU - Faivre-Finn, Corinne
AU - Badiyan, Shahed N.
N1 - Publisher Copyright:
© 2021
PY - 2021/7
Y1 - 2021/7
N2 - Stereotactic body radiation therapy (SBRT) is an effective and well-tolerated treatment for medically inoperable patients with early stage NSCLC. SBRT is a noninvasive treatment involving the delivery of ablative radiation doses with high precision in the course of a few treatments. Relative to conventionally fractionated radiation, SBRT achieves superior local control and survival. SBRT use has increased dramatically in the past 15 years and is currently considered the standard of care in cases of inoperable early stage NSCLC. It is being increasingly applied to more complex patient populations at higher risk of treatment-related toxicity. In these more complex patients, there is an increasing need to balance patient and treatment factors in selecting the optimal patients for SBRT. Here, we review several challenging clinical scenarios often encountered in thoracic multidisciplinary tumor boards.
AB - Stereotactic body radiation therapy (SBRT) is an effective and well-tolerated treatment for medically inoperable patients with early stage NSCLC. SBRT is a noninvasive treatment involving the delivery of ablative radiation doses with high precision in the course of a few treatments. Relative to conventionally fractionated radiation, SBRT achieves superior local control and survival. SBRT use has increased dramatically in the past 15 years and is currently considered the standard of care in cases of inoperable early stage NSCLC. It is being increasingly applied to more complex patient populations at higher risk of treatment-related toxicity. In these more complex patients, there is an increasing need to balance patient and treatment factors in selecting the optimal patients for SBRT. Here, we review several challenging clinical scenarios often encountered in thoracic multidisciplinary tumor boards.
KW - Interstitial lung disease
KW - Non–small cell lung cancer
KW - Oligometastatic
KW - Reirradiation
KW - Stereotactic body radiation therapy
KW - Ultracentral
UR - http://www.scopus.com/inward/record.url?scp=85106961873&partnerID=8YFLogxK
U2 - 10.1016/j.jtho.2021.04.002
DO - 10.1016/j.jtho.2021.04.002
M3 - Review article
C2 - 33901637
AN - SCOPUS:85106961873
SN - 1556-0864
VL - 16
SP - 1075
EP - 1085
JO - Journal of Thoracic Oncology
JF - Journal of Thoracic Oncology
IS - 7
ER -