Stereotactic external beam irradiation using a linear accelerator: the Washington University experience.

J. R. Simpson, K. M. Rich, R. E. Drzymala, T. H. Wasserman, E. E. Klein, M. Michaletz-Lorenz, J. Maurath, E. Filiput

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Abstract

From February 1989 to December 1993, 139 patients with a variety of brain lesions were treated with stereotactic external beam irradiation using a 6MV linear accelerator. The largest group consisted of patients with recurrent brain metastases (n = 46). Twenty seven patients had malignant gliomas, most of which were recurrent. Several benign conditions were treated, including arteriovenous malformations (n = 27), acoustic neuromas (n = 9), meningiomas (n = 7), and pituitary adenomas (n = 2). Durable responses were seen in the majority of patients with transient, mild, side effects. This experience suggests that stereotactic external beam irradiation is a safe, reliable, and effective method for non-invasive treatment of selected patients with small, localized brain lesions.

Original languageEnglish
Pages (from-to)188-192
Number of pages5
JournalMissouri Medicine
Volume92
Issue number4
StatePublished - Apr 1995

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    Simpson, J. R., Rich, K. M., Drzymala, R. E., Wasserman, T. H., Klein, E. E., Michaletz-Lorenz, M., Maurath, J., & Filiput, E. (1995). Stereotactic external beam irradiation using a linear accelerator: the Washington University experience. Missouri Medicine, 92(4), 188-192.