Stereotactic external beam irradiation using a linear accelerator: the Washington University experience.

J. R. Simpson; K. M. Rich; R. E. Drzymala; T. H. Wasserman; E. E. Klein; M. Michaletz-Lorenz; J. Maurath; E. Filiput

Stereotactic external beam irradiation using a linear accelerator: the Washington University experience.

J. R. Simpson, K. M. Rich, R. E. Drzymala, T. H. Wasserman, E. E. Klein, M. Michaletz-Lorenz, J. Maurath, E. Filiput

Department of Neurosurgery

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

From February 1989 to December 1993, 139 patients with a variety of brain lesions were treated with stereotactic external beam irradiation using a 6MV linear accelerator. The largest group consisted of patients with recurrent brain metastases (n = 46). Twenty seven patients had malignant gliomas, most of which were recurrent. Several benign conditions were treated, including arteriovenous malformations (n = 27), acoustic neuromas (n = 9), meningiomas (n = 7), and pituitary adenomas (n = 2). Durable responses were seen in the majority of patients with transient, mild, side effects. This experience suggests that stereotactic external beam irradiation is a safe, reliable, and effective method for non-invasive treatment of selected patients with small, localized brain lesions.

Original language	English
Pages (from-to)	188-192
Number of pages	5
Journal	Missouri Medicine
Volume	92
Issue number	4
State	Published - Apr 1995

Cite this

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title = "Stereotactic external beam irradiation using a linear accelerator: the Washington University experience.",

abstract = "From February 1989 to December 1993, 139 patients with a variety of brain lesions were treated with stereotactic external beam irradiation using a 6MV linear accelerator. The largest group consisted of patients with recurrent brain metastases (n = 46). Twenty seven patients had malignant gliomas, most of which were recurrent. Several benign conditions were treated, including arteriovenous malformations (n = 27), acoustic neuromas (n = 9), meningiomas (n = 7), and pituitary adenomas (n = 2). Durable responses were seen in the majority of patients with transient, mild, side effects. This experience suggests that stereotactic external beam irradiation is a safe, reliable, and effective method for non-invasive treatment of selected patients with small, localized brain lesions.",

author = "Simpson, {J. R.} and Rich, {K. M.} and Drzymala, {R. E.} and Wasserman, {T. H.} and Klein, {E. E.} and M. Michaletz-Lorenz and J. Maurath and E. Filiput",

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AU - Rich, K. M.

AU - Drzymala, R. E.

AU - Wasserman, T. H.

AU - Klein, E. E.

AU - Michaletz-Lorenz, M.

AU - Maurath, J.

AU - Filiput, E.

PY - 1995/4

Y1 - 1995/4

N2 - From February 1989 to December 1993, 139 patients with a variety of brain lesions were treated with stereotactic external beam irradiation using a 6MV linear accelerator. The largest group consisted of patients with recurrent brain metastases (n = 46). Twenty seven patients had malignant gliomas, most of which were recurrent. Several benign conditions were treated, including arteriovenous malformations (n = 27), acoustic neuromas (n = 9), meningiomas (n = 7), and pituitary adenomas (n = 2). Durable responses were seen in the majority of patients with transient, mild, side effects. This experience suggests that stereotactic external beam irradiation is a safe, reliable, and effective method for non-invasive treatment of selected patients with small, localized brain lesions.

AB - From February 1989 to December 1993, 139 patients with a variety of brain lesions were treated with stereotactic external beam irradiation using a 6MV linear accelerator. The largest group consisted of patients with recurrent brain metastases (n = 46). Twenty seven patients had malignant gliomas, most of which were recurrent. Several benign conditions were treated, including arteriovenous malformations (n = 27), acoustic neuromas (n = 9), meningiomas (n = 7), and pituitary adenomas (n = 2). Durable responses were seen in the majority of patients with transient, mild, side effects. This experience suggests that stereotactic external beam irradiation is a safe, reliable, and effective method for non-invasive treatment of selected patients with small, localized brain lesions.

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Stereotactic external beam irradiation using a linear accelerator: the Washington University experience.

Abstract

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