TY - JOUR
T1 - Stereopsis activates V3A and caudal intraparietal areas in macaques and humans
AU - Tsao, Doris Y.
AU - Vanduffel, Wim
AU - Sasaki, Yuka
AU - Fize, Denis
AU - Knutsen, Tamara A.
AU - Mandeville, Joseph B.
AU - Wald, Lawrence L.
AU - Dale, Anders M.
AU - Rosen, Bruce R.
AU - Van Essen, David C.
AU - Livingstone, Margaret S.
AU - Orban, Guy A.
AU - Tootell, Roger B.H.
N1 - Funding Information:
We are grateful to Egon Pasztor for building the barrel chair and to Doug Greve, Bruce Fischl, Rick Hoge, Don Rogers, Mike Lafratta, Koen Nelissen, and Katrien Denys for technical support. Greg DeAngelis, James Lewis, David Hubel, Bevil Conway, Winrich Freiwald, and Robert Savoy provided helpful discussions and comments on the manuscript. This work was supported by grants from the MIND Institute, NIH (1RO1MH67529), BRP (1RO1EB00790), the Queen Elisabeth Foundation (GSKE), NFWO (G3106.94 and G0112.00), GOA (95/6 and 2000/11), and IUAP (4/22).
PY - 2003/7/31
Y1 - 2003/7/31
N2 - Stereopsis, the perception of depth from small differences between the images in the two eyes, provides a rich model for investigating the cortical construction of surfaces and space. Although disparity-tuned cells have been found in a large number of areas in macaque visual cortex, stereoscopic processing in these areas has never been systematically compared using the same stimuli and analysis methods. In order to examine the global architecture of stereoscopic processing in primate visual cortex, we studied fMRI activity in alert, fixating human and macaque subjects. In macaques, we found strongest activation to near/far compared to zero disparity in areas V3, V3A, and CIPS. In humans, we found strongest activation to the same stimuli in areas V3A, V7, the V4d topolog (V4d-topo), and a caudal parietal disparity region (CPDR). Thus, in both primate species a small cluster of areas at the parieto-occipital junction appears to be specialized for stereopsis.
AB - Stereopsis, the perception of depth from small differences between the images in the two eyes, provides a rich model for investigating the cortical construction of surfaces and space. Although disparity-tuned cells have been found in a large number of areas in macaque visual cortex, stereoscopic processing in these areas has never been systematically compared using the same stimuli and analysis methods. In order to examine the global architecture of stereoscopic processing in primate visual cortex, we studied fMRI activity in alert, fixating human and macaque subjects. In macaques, we found strongest activation to near/far compared to zero disparity in areas V3, V3A, and CIPS. In humans, we found strongest activation to the same stimuli in areas V3A, V7, the V4d topolog (V4d-topo), and a caudal parietal disparity region (CPDR). Thus, in both primate species a small cluster of areas at the parieto-occipital junction appears to be specialized for stereopsis.
UR - http://www.scopus.com/inward/record.url?scp=0042697232&partnerID=8YFLogxK
U2 - 10.1016/S0896-6273(03)00459-8
DO - 10.1016/S0896-6273(03)00459-8
M3 - Article
C2 - 12895427
AN - SCOPUS:0042697232
VL - 39
SP - 555
EP - 568
JO - Neuron
JF - Neuron
SN - 0896-6273
IS - 3
ER -