Stealth Attack: Plaque-Specific Antibody Allows for Efficient Aβ Removal without Side Effects

Jee Hoon Roh, David M. Holtzman

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

Anti-Aβ antibodies are being developed as potential treatments for Alzheimer's disease. Some have dose-limiting side effects and many do not robustly remove pre-existing amyloid plaques. In this issue of Neuron, DeMattos et al. (2012) demonstrate that an amyloid plaque-specific antibody removes existing Aβ aggregates without side effects.

Original languageEnglish
Pages (from-to)859-861
Number of pages3
JournalNeuron
Volume76
Issue number5
DOIs
StatePublished - Dec 6 2012

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