Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data

Keyphrases

• Cancer Genes 100%
• Tumor Suppressor 100%
• Genome Sequencing 100%
• Oncogene 100%
• Cancer Genome Sequencing 100%
• Pan-cancer 100%
• Tumor Suppressor Gene 40%
• Performance Improvement 40%
• Area under the Receiver Operating Characteristic (AUROC) 40%
• Mutation Data 40%
• Somatic mutation 20%
• Loss Function 20%
• Statistical Test 20%
• Truncation 20%
• Mechanism of Action 20%
• Event Rate 20%
• Gain-of-function 20%
• Improved Detection 20%
• Cancer Detection 20%
• Gene-based 20%
• Cancer Driver Genes 20%
• Random Forest 20%
• Cancer Dataset 20%
• Gene Panel 20%
• HLA-DRB1 20%
• GitHub 20%
• Histone Deacetylase 2 (HDAC2) 20%
• NXF1 20%
• Cancer Gene Discovery 20%
• GPS2 20%
• HIST1H1E 20%
• Patient Bias 20%

Biochemistry, Genetics and Molecular Biology

• Tumor Suppressor Protein 100%
• Oncogene 100%
• Cancer Genome Sequencing 100%
• Pan-cancer 100%
• Tumor Suppressor Gene 22%
• Somatic Mutation 11%
• Gene Discovery 11%
• Tumor Gene 11%
• Statistical Test 11%
• Random Forest 11%
• HLA-DRB1 11%
• Histone Deacetylase 2 11%