Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress

Keyphrases

• Null Mice 100%
• Oxidative Stress 100%
• Ionizing Radiation 100%
• Mutational Patterns 100%
• Immortalized Cell 100%
• Mouse Model 33%
• Primary Culture 33%
• Kidney 33%
• Adult Mice 33%
• Mutational Analysis 33%
• Cell Culture 33%
• Null Cell 33%
• Knock-in mutation 33%
• Ataxia Telangiectasia 33%
• Loss of Expression 33%
• Mutagenic Effects 33%
• Permanent Cell Line 33%
• Autosomal Genes 33%
• Chronic Oxidative Stress 33%
• Spontaneous mutant 33%
• Cell Cycle Defects 33%
• Oxidative mutagenesis 33%

Neuroscience

• Oxidative Stress 100%
• Immortalised Cell Line 100%
• In Vivo 50%
• Primary Culture 50%
• Cell Line 50%
• Cell Culture 50%
• Cell Cycle 50%
• Ataxia Telangiectasia 50%
• Mutagenesis 50%