Spontaneous redistribution of surface immunoglobulin in the motile b lymphocyte*

George F. Schreiner, Jonathan Braun, Emil R. Unanue

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


This paper reports that B cells undergoing translatory motion spontaneously segregate their surface Ig to one portion of their plasma membrane. The spontaneous redistribution of surface Ig was found to be: (a) selective, concanavalin Abinding sites and H-2 antigens were not redistributed; and (b) absolutely dependent on translatory motion and energy metabolism. Abundant B cells undergoing motility were found after cultures in lipopolysaccharide or trypsin, or after brief exposure to cholinergic drugs.

Original languageEnglish
Pages (from-to)1683-1688
Number of pages6
JournalJournal of Experimental Medicine
Issue number6
StatePublished - Dec 1 1976


Dive into the research topics of 'Spontaneous redistribution of surface immunoglobulin in the motile b lymphocyte*'. Together they form a unique fingerprint.

Cite this