TY - JOUR
T1 - Spontaneous redistribution of surface immunoglobulin in the motile b lymphocyte*
AU - Schreiner, George F.
AU - Braun, Jonathan
AU - Unanue, Emil R.
PY - 1976/12/1
Y1 - 1976/12/1
N2 - This paper reports that B cells undergoing translatory motion spontaneously segregate their surface Ig to one portion of their plasma membrane. The spontaneous redistribution of surface Ig was found to be: (a) selective, concanavalin Abinding sites and H-2 antigens were not redistributed; and (b) absolutely dependent on translatory motion and energy metabolism. Abundant B cells undergoing motility were found after cultures in lipopolysaccharide or trypsin, or after brief exposure to cholinergic drugs.
AB - This paper reports that B cells undergoing translatory motion spontaneously segregate their surface Ig to one portion of their plasma membrane. The spontaneous redistribution of surface Ig was found to be: (a) selective, concanavalin Abinding sites and H-2 antigens were not redistributed; and (b) absolutely dependent on translatory motion and energy metabolism. Abundant B cells undergoing motility were found after cultures in lipopolysaccharide or trypsin, or after brief exposure to cholinergic drugs.
UR - http://www.scopus.com/inward/record.url?scp=0017035297&partnerID=8YFLogxK
U2 - 10.1084/jem.144.6.1683
DO - 10.1084/jem.144.6.1683
M3 - Article
C2 - 1087328
AN - SCOPUS:0017035297
SN - 0022-1007
VL - 144
SP - 1683
EP - 1688
JO - Journal of Experimental Medicine
JF - Journal of Experimental Medicine
IS - 6
ER -