TY - JOUR
T1 - Spindle cell sarcomatoid carcinoma of the trachea
T2 - First case report of surgical resection
AU - Gurria, Juan P.
AU - De Acosta, David M.
AU - Hafezi, Niloufar
AU - Yousif, Eman B.
AU - AlAmeer, Ehab
AU - Anderson, Richard C.
N1 - Publisher Copyright:
© 2016 The Author(s).
PY - 2016/8/5
Y1 - 2016/8/5
N2 - Background: Primary malignant tracheal tumors are rare, accounting for approximately 0.2 % of respiratory tract tumors yearly, with squamous cell carcinomas and adenoid cystic carcinomas accounting for two-thirds of these cases. Sarcomatoid carcinomas are a group of poorly differentiated non-small cell lung carcinomas containing a component of sarcoma or sarcoma-like (spindle and/or giant cell) differentiation, categorized into five morphologic subgroups. Spindle cell sarcomatoid carcinoma is a rare variant of sarcomatoid carcinomas, consisting of only spindle-shaped tumor cells. Only one other case has been reported as a primary tracheal tumor. Case presentation: We present a 75-year-old male, having progressive dyspnea and cough, with a spindle cell sarcomatoid carcinoma tumor visualized on chest computed tomography scan and confirmed with biopsy. Conclusions: Due to its low incidence, knowledge of treatment methods, prognostic factors, and etiology is limited thus approaches to eradication have widely varied. We are reporting the second published case of spindle cell sarcomatoid carcinoma of the trachea and the first reported successful outcome of definitive treatment with tracheal resection.
AB - Background: Primary malignant tracheal tumors are rare, accounting for approximately 0.2 % of respiratory tract tumors yearly, with squamous cell carcinomas and adenoid cystic carcinomas accounting for two-thirds of these cases. Sarcomatoid carcinomas are a group of poorly differentiated non-small cell lung carcinomas containing a component of sarcoma or sarcoma-like (spindle and/or giant cell) differentiation, categorized into five morphologic subgroups. Spindle cell sarcomatoid carcinoma is a rare variant of sarcomatoid carcinomas, consisting of only spindle-shaped tumor cells. Only one other case has been reported as a primary tracheal tumor. Case presentation: We present a 75-year-old male, having progressive dyspnea and cough, with a spindle cell sarcomatoid carcinoma tumor visualized on chest computed tomography scan and confirmed with biopsy. Conclusions: Due to its low incidence, knowledge of treatment methods, prognostic factors, and etiology is limited thus approaches to eradication have widely varied. We are reporting the second published case of spindle cell sarcomatoid carcinoma of the trachea and the first reported successful outcome of definitive treatment with tracheal resection.
KW - Carcinoma
KW - Resection
KW - Sarcomatoid
KW - Spindle cell
KW - Trachea
KW - Tumor
UR - http://www.scopus.com/inward/record.url?scp=84988628776&partnerID=8YFLogxK
U2 - 10.1186/s13019-016-0524-x
DO - 10.1186/s13019-016-0524-x
M3 - Article
C2 - 27495807
AN - SCOPUS:84988628776
SN - 1749-8090
VL - 11
JO - Journal of Cardiothoracic Surgery
JF - Journal of Cardiothoracic Surgery
IS - 1
M1 - 128
ER -