TY - JOUR
T1 - Spinal Tumors
T2 - Diagnosis and Treatment
AU - Goodwin, Matthew L.
AU - Buchowski, Jacob M.
AU - Schwab, Joseph H.
AU - Sciubba, Daniel M.
N1 - Funding Information:
Goodwin or an immediate family member receives royalties from Kendall Hunt publishing; serves as consultant to Augmedics; serves as consultant and has stock held in ROM3; has received fellowship support from AO Spine/Globus; and has stock held in Pfizer, BioNTech, Moderna, and Johnson and Johnson. Buchowski or an immediate family member receives royalties from Globus Medical and K2M/Stryker and has received institutional fellowship support from AO North America and OMeGA. Schwab or an immediate family member serves on a scientific advisory board of the Chordoma Foundation. Sciubba or an immediate family member serves as a consultant to DePuy-Synthes, Medtronic, Stryker, and Baxter; has stock held in Augmedics; and is an equity owner of BioPhy. All authors serve on the North American spine society (NASS) spine oncology subcommittee.
Publisher Copyright:
© American Academy of Orthopaedic Surgeons.
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Tumors that present in or around the spine can be challenging to diagnose and treat. A proper workup involves a complete history and physical examination, appropriate staging studies, appropriate imaging of the entire spine, and a tissue biopsy. The biopsy defines the lesion and guides treatment, but in some rare instances, rapid neurological decline may lead to urgent or emergent surgery before it can be analyzed. "Enneking-appropriate"margins should remain the goal for primary tumors while adequate debulking/separation/stabilization are often the goals in metastatic disease. Primary tumors of the spine are rare and often complex tumors to operate on - achieving Enneking-appropriate margins provides the greatest chance of survival while decreasing the chance of local recurrence. Metastatic tumors of the spine are increasingly more common, and timing of surgery must be considered within the greater framework of the patient and the patient's disease, deficits, stability, and other treatments available. The specific tumor type will dictate what other multidisciplinary approaches are available, allowing for chemotherapy and radiation as needed.
AB - Tumors that present in or around the spine can be challenging to diagnose and treat. A proper workup involves a complete history and physical examination, appropriate staging studies, appropriate imaging of the entire spine, and a tissue biopsy. The biopsy defines the lesion and guides treatment, but in some rare instances, rapid neurological decline may lead to urgent or emergent surgery before it can be analyzed. "Enneking-appropriate"margins should remain the goal for primary tumors while adequate debulking/separation/stabilization are often the goals in metastatic disease. Primary tumors of the spine are rare and often complex tumors to operate on - achieving Enneking-appropriate margins provides the greatest chance of survival while decreasing the chance of local recurrence. Metastatic tumors of the spine are increasingly more common, and timing of surgery must be considered within the greater framework of the patient and the patient's disease, deficits, stability, and other treatments available. The specific tumor type will dictate what other multidisciplinary approaches are available, allowing for chemotherapy and radiation as needed.
UR - http://www.scopus.com/inward/record.url?scp=85136081650&partnerID=8YFLogxK
U2 - 10.5435/JAAOS-D-21-00710
DO - 10.5435/JAAOS-D-21-00710
M3 - Review article
C2 - 35984082
AN - SCOPUS:85136081650
SN - 1067-151X
VL - 30
SP - E1106-E1121
JO - Journal of the American Academy of Orthopaedic Surgeons
JF - Journal of the American Academy of Orthopaedic Surgeons
IS - 17
ER -