@article{030f83c2ff6b4923a63933dae0299e01,
title = "SpeedSeq: Ultra-fast personal genome analysis and interpretation",
abstract = "SpeedSeq is an open-source genome analysis platform that accomplishes alignment, variant detection and functional annotation of a 50× human genome in 13 h on a low-cost server and alleviates a bioinformatics bottleneck that typically demands weeks of computation with extensive hands-on expert involvement. SpeedSeq offers performance competitive with or superior to current methods for detecting germline and somatic single-nucleotide variants, structural variants, insertions and deletions, and it includes novel functionality for streamlined interpretation.",
author = "Colby Chiang and Layer, {Ryan M.} and Faust, {Gregory G.} and Lindberg, {Michael R.} and Rose, {David B.} and Garrison, {Erik P.} and Marth, {Gabor T.} and Quinlan, {Aaron R.} and Hall, {Ira M.}",
note = "Funding Information: The authors thank A. Abyzov for helpful discussions about CNVnator. This work was supported by US National Institutes of Health (NIH) training grant T32 GM007267 (C.C.), NIH NHGRI grant R01HG006693 (A.R.Q.), and NIH NHGRI center grant U54 HG003079, NIH New Innovator Award DP2OD006493-01 and a Burroughs Wellcome Fund Career Award (I.M.H.). Publisher Copyright: {\textcopyright} 2015 Nature America, Inc. All rights reserved.",
year = "2015",
month = sep,
day = "29",
doi = "10.1038/nmeth.3505",
language = "English",
volume = "12",
pages = "966--968",
journal = "Nature Methods",
issn = "1548-7091",
number = "10",
}