Spectral tuning of azobenzene photoswitches for biological applications

Oleg Sadovski; Andrew A. Beharry; Fuzhong Zhang; G. Andrew Woolley

doi:10.1002/anie.200805013

Spectral tuning of azobenzene photoswitches for biological applications

Oleg Sadovski, Andrew A. Beharry, Fuzhong Zhang, G. Andrew Woolley

Research output: Contribution to journal › Article › peer-review

176 Scopus citations

Abstract

Longer switching wavelengths and good photochemical yields and stabilities of the cis isomers in reducing aqueous environments are achieved by introducing 2,2 -aminoalkyl substituents into 4,4 - diamido-substituted azobenzenes. The products are thus suitable for photocontrol of biomolecular structures in intracellular environments, such as switching between two peptide configurations (see pictures).

Original language	English
Pages (from-to)	1484-1486
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	8
DOIs	https://doi.org/10.1002/anie.200805013
State	Published - Feb 9 2009

Keywords

azo compounds
Isomerization
Peptides
Photoswitches

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10.1002/anie.200805013

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abstract = "Longer switching wavelengths and good photochemical yields and stabilities of the cis isomers in reducing aqueous environments are achieved by introducing 2,2 -aminoalkyl substituents into 4,4 - diamido-substituted azobenzenes. The products are thus suitable for photocontrol of biomolecular structures in intracellular environments, such as switching between two peptide configurations (see pictures).",

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AU - Sadovski, Oleg

AU - Beharry, Andrew A.

AU - Zhang, Fuzhong

AU - Woolley, G. Andrew

PY - 2009/2/9

Y1 - 2009/2/9

N2 - Longer switching wavelengths and good photochemical yields and stabilities of the cis isomers in reducing aqueous environments are achieved by introducing 2,2 -aminoalkyl substituents into 4,4 - diamido-substituted azobenzenes. The products are thus suitable for photocontrol of biomolecular structures in intracellular environments, such as switching between two peptide configurations (see pictures).

AB - Longer switching wavelengths and good photochemical yields and stabilities of the cis isomers in reducing aqueous environments are achieved by introducing 2,2 -aminoalkyl substituents into 4,4 - diamido-substituted azobenzenes. The products are thus suitable for photocontrol of biomolecular structures in intracellular environments, such as switching between two peptide configurations (see pictures).

KW - azo compounds

KW - Isomerization

KW - Peptides

KW - Photoswitches

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DO - 10.1002/anie.200805013

M3 - Article

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AN - SCOPUS:60149097223

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

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ER -

Spectral tuning of azobenzene photoswitches for biological applications

Abstract

Keywords

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