TY - JOUR
T1 - Speckle contrast optical tomography
T2 - A new method for deep tissue three-dimensional tomography of blood flow
AU - Varma, Hari M.
AU - Valdes, Claudia P.
AU - Kristoffersen, Anna K.
AU - Culver, Joseph P.
AU - Durduran, Turgut
PY - 2014/4/1
Y1 - 2014/4/1
N2 - A novel tomographic method based on the laser speckle contrast, speckle contrast optical tomography (SCOT) is introduced that allows us to reconstruct three dimensional distribution of blood flow in deep tissues. This method is analogous to the diffuse optical tomography (DOT) but for deep tissue blood flow.We develop a reconstruction algorithm based on first Born approximation to generate three dimensional distribution of flow using the experimental data obtained from tissue simulating phantoms.
AB - A novel tomographic method based on the laser speckle contrast, speckle contrast optical tomography (SCOT) is introduced that allows us to reconstruct three dimensional distribution of blood flow in deep tissues. This method is analogous to the diffuse optical tomography (DOT) but for deep tissue blood flow.We develop a reconstruction algorithm based on first Born approximation to generate three dimensional distribution of flow using the experimental data obtained from tissue simulating phantoms.
UR - http://www.scopus.com/inward/record.url?scp=84898984578&partnerID=8YFLogxK
U2 - 10.1364/BOE.5.001275
DO - 10.1364/BOE.5.001275
M3 - Article
C2 - 24761306
AN - SCOPUS:84898984578
SN - 2156-7085
VL - 5
SP - 1062?1074
JO - Biomedical Optics Express
JF - Biomedical Optics Express
IS - 4
ER -