Specific Killing of Ph⁺ Chronic Myeloid Leukemia Cells by a Lentiviral Vector-Delivered Anti-bcr/abl Small Hairpin RNA

Keyphrases

• Short Hairpin RNA (shRNA) 100%
• Chronic Myeloid Leukemia 100%
• Lentiviral Vector 100%
• Myeloid Leukemia Cells 100%
• BCR-ABL 100%
• Leukemia Cells 20%
• Tyrosine Kinase Activity 20%
• Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) 20%
• Fusion Gene 20%
• Inhibition Rate 20%
• Oncoprotein 20%
• Chromosome 22 20%
• Chromosome 9 20%
• Splice Variant 20%
• Reciprocal Translocation 20%
• P210 20%
• Philadelphia Chromosome 20%
• Proliferation Inhibition 20%
• K562 Leukemia Cells 20%
• Ex Vivo Purging 20%

Biochemistry, Genetics and Molecular Biology

• Myeloid 100%
• Small Hairpin RNA 100%
• Lentivirus Vector 100%
• Downregulation 20%
• Receptor Tyrosine Kinase 20%
• Tyrosine Kinase 20%
• Chromosomal Translocation 20%
• Fusion Gene 20%
• Transcription 20%
• Oncogene 20%
• Chromosome 22 20%
• Chromosome 9 20%
• Cell pH 20%
• Philadelphia Chromosome 20%
• Hematopoietic Cell 20%