Specific Immunofluorescence Test for Detection of Herpesvirus Antigen in Cells of the Lucke Renal Adenocarcinoma

Steven M. Paul, Merle Mizell, Branch Craige, Julia Blazek, Margaret Skinner

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Antiserum prepared against purified herpesvirus fractions of the Lucké tumor has been used in detecting the virus-containing nature of various tumor samples. Bright fluorescence of winter tumor cells was observed when reacted in the indirect immunofluorescence test with the prepared antiserum. No staining was observed in tumor samples not harboring the herpesvirus or in normal frog kidney sections. The evidence that the antiserum is specific for a frog herpesvirus antigen(s) is discussed.

Original languageEnglish
Pages (from-to)944-948
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume139
Issue number3
DOIs
StatePublished - Mar 1972
Externally publishedYes

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