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Spatiotemporal Control of CNS Myelination by Oligodendrocyte Programmed Cell Death through the TFEB-PUMA Axis
Lu O. Sun
, Sara B. Mulinyawe
, Hannah Y. Collins
, Adiljan Ibrahim
,
Qingyun Li
, David J. Simon
, Marc Tessier-Lavigne
, Ben A. Barres
Department of Neuroscience
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Department of Genetics
Center of Regenerative Medicine
Institute of Clinical and Translational Sciences (ICTS)
DBBS - Neurosciences
DBBS - Developmental, Regenerative and Stem Cell Biology
DBBS - Molecular Genetics and Genomics
Hope Center for Neurological Disorders
Research output
:
Contribution to journal
›
Article
›
peer-review
104
Scopus citations
Overview
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Keyphrases
Oligodendrocyte
100%
Myelination
100%
Programmed Cell Death
100%
Transcription Factor EB
100%
CNS Myelination
100%
Spatiotemporal Control
100%
Brain Regions
50%
Nervous System
50%
Molecular Mechanism
25%
Axon
25%
Intrinsic Mechanism
25%
System Function
25%
Unmyelinated
25%
Regional Specificity
25%
Trophic Support
25%
Temporal Specificity
25%
Bak Activation
25%
Myelinating Glia
25%
Premyelinating Oligodendrocytes
25%
Insulation
25%
Selective Elimination
25%
Spatiotemporal Specificity
25%
Neuroscience
Oligodendrocyte
100%
Cell Death
100%
Transcription Factors
100%
Myelinogenesis
100%
Glia
14%
Cell Function
14%
Nervous System
14%
Brain Areas
14%
Nervous System Function
14%
Axon
14%
Brain Region
14%