Somatic mosaicism in Menkes disease suggests choroid plexus-mediated copper transport to the developing brain

Keyphrases

• Brain Development 100%
• Ectoderm 100%
• Choroid Plexus 100%
• Copper Transport 100%
• Menkes Disease 100%
• Somatic Mosaicism 100%
• Mesoderm 66%
• Angioblast 66%
• ATP7A 66%
• Choroid Plexus Epithelial Cells 66%
• Mesodermal 66%
• Blood-cerebrospinal Fluid Barrier 66%
• Brain Capillary Endothelial Cells 66%
• Cerebrospinal Fluid 33%
• Central Nervous System 33%
• Blood-brain Barrier 33%
• Catecholamines 33%
• Gastrulation 33%
• Evolutionarily Conserved 33%
• Severe Phenotype 33%
• Missense mutation 33%
• Endoderm 33%
• X-linked 33%
• Cultured Fibroblasts 33%
• Blood Cells 33%
• Neurodevelopmental Disorders 33%
• Mosaicism 33%
• Embryonic Origin 33%
• DNA Samples 33%
• Biochemical Detection 33%
• Neuroectoderm 33%
• Entry Route 33%
• Copper Transporter 33%
• Copper Treatment 33%
• Blood Copper 33%
• ATP7A Gene 33%

Biochemistry, Genetics and Molecular Biology

• Mosaicism 100%
• Ectoderm 100%
• Epiblast 100%
• ATP7A 100%
• Menkes Disease 100%
• Mesoderm 66%
• Angioblast 66%
• Blood Cerebrospinal Fluid Barrier 66%
• Allele 33%
• Liquid 33%
• Gastrulation 33%
• Missense Mutation 33%
• Endoderm 33%
• Blood Brain Barrier 33%
• Catecholamine Blood Level 33%
• Neural Plate 33%
• Copper Blood Level 33%
• Fibroblast 33%