@inproceedings{ae3460c918964bd192874bfbe6cbe4d5,
title = "Soft lithography-based hydrogel particles and the effect of shape and size on biodistribution",
abstract = "Poor solubility and rapid elimination can make small-molecule therapeutics difficult to deliver. In addition, many old therapies are in need of repackaging. In order to overcome these obstacles we have employed a top-down particle fabrication technique called Particle Replication In Non-wetting Templates (PRINT{\textregistered}) to fabricate unique biocompatible particles with distinct therapeutic properties based on their composition, size, shape and cargo. Particles were tagged with a variety of imaging beacons making them effective as contrast agents for magnetic resonance imaging and fluorescence imaging. After tail vein injection balb-c mice were imaged by magnetic resonance imaging and near infrared fluorescence imaging.",
keywords = "Biodistribution, Contrast agent, MRI, Nanoparticle, PRINT",
author = "K. Herlihy and T. Merkel and Hongyu An and Weili Lin and J. Desimone",
year = "2009",
month = dec,
day = "1",
language = "English",
isbn = "9781439817834",
series = "Technical Proceedings of the 2009 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2009",
pages = "60--63",
booktitle = "Technical Proceedings of the 2009 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2009",
note = "Nanotechnology 2009: Life Sciences, Medicine, Diagnostics, Bio Materials and Composites - 2009 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2009 ; Conference date: 03-05-2009 Through 07-05-2009",
}