Sodium 4-phenylbutyrate downregulates HSC70 expression by facilitating mRNA degradation

Keyphrases

• RNA Degradation 100%
• Hsc70 100%
• Sodium 4-phenylbutyrate 100%
• 4-phenylbutyrate 66%
• Cystic Fibrosis Transmembrane Conductance Regulator 25%
• MRNA Expression 16%
• Protein Expression 16%
• Steady State 16%
• MRNA Level 8%
• Chinese Hamster Ovary Cells 8%
• RNA Synthesis 8%
• Protein Synthesis 8%
• Pre-incubation 8%
• Protein Family 8%
• Heat Shock Proteins 8%
• Intracellular Degradation 8%
• Degradation Rate 8%
• Cellular Adaptation 8%
• 70-kDa Heat Shock Protein 8%
• Intracellular Trafficking 8%
• Luciferase Reporter Assay 8%

Biochemistry, Genetics and Molecular Biology

• Messenger RNA 100%
• Cystic Fibrosis Transmembrane Conductance Regulator 42%
• Promoter Region 28%
• Steady State 28%
• Luciferase 14%
• Protein Expression 14%
• Heat Shock Protein 14%
• Protein Family 14%
• Chinese Hamster 14%
• Protein Biosynthesis 14%
• Messenger RNA Synthesis 14%
• Heat Shock 14%
• Intracellular Trafficking 14%