Socioeconomic status is independently associated with overall survival in patients with multiple myeloma

Mark A. Fiala, Joseph D. Finney, Jingxia Liu, Keith E. Stockerl-Goldstein, Michael H. Tomasson, Ravi Vij, Tanya M. Wildes

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Population-based studies suggest that black patients with multiple myeloma (MM) have a higher mortality rate than white patients. However, other studies suggest that this disparity is related to socioeconomic status (SES) rather than race. To provide clarity on this topic, we reviewed 562 patients diagnosed with MM at our institution. Patients with high SES had a median overall survival (OS) of 62.8 months (95% confidence interval [CI] 43.1-82.6 months), compared to 53.7 months (45.2-62.3 months) and 48.6 months (40.4-56.8 months) for middle and low SES, respectively (p = 0.015). After controlling for race, age, year of diagnosis, severity of comorbidities, stem cell transplant utilization and insurance provider, patients with low SES had a 54% increase in mortality rate relative to patients with high SES. To support our findings, we performed a similar analysis of 45,505 patients with MM from the Surveillance, Epidemiology and End Results-18 (SEER) database. Low SES is independently associated with poorer OS in MM.

Original languageEnglish
Pages (from-to)2643-2649
Number of pages7
JournalLeukemia and Lymphoma
Volume56
Issue number9
DOIs
StatePublished - Sep 2 2015

Keywords

  • Multiple myeloma
  • cancer health disparities
  • race
  • socioeconomic status

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