Soaping up transcriptional condensates

Min Kyung Shinn; Rohit V. Pappu

doi:10.1016/j.devcel.2023.05.002

Soaping up transcriptional condensates

Min Kyung Shinn, Rohit V. Pappu

Research output: Contribution to journal › Comment/debate

2 Scopus citations

Abstract

The condensate-forming ability of transcription factors (TFs) has received considerable attention, although how condensates function in transcription remains unclear. In this issue of Developmental Cell, Wang et al. show that target DNA and transcriptional regulators work as soap-like surfactants to adsorb on condensates, affecting the activities of transcriptional condensates.

Original language	English
Pages (from-to)	915-916
Number of pages	2
Journal	Developmental cell
Volume	58
Issue number	11
DOIs	https://doi.org/10.1016/j.devcel.2023.05.002
State	Published - Jun 5 2023

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title = "Soaping up transcriptional condensates",

abstract = "The condensate-forming ability of transcription factors (TFs) has received considerable attention, although how condensates function in transcription remains unclear. In this issue of Developmental Cell, Wang et al. show that target DNA and transcriptional regulators work as soap-like surfactants to adsorb on condensates, affecting the activities of transcriptional condensates.",

author = "Shinn, {Min Kyung} and Pappu, {Rohit V.}",

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AU - Shinn, Min Kyung

AU - Pappu, Rohit V.

PY - 2023/6/5

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N2 - The condensate-forming ability of transcription factors (TFs) has received considerable attention, although how condensates function in transcription remains unclear. In this issue of Developmental Cell, Wang et al. show that target DNA and transcriptional regulators work as soap-like surfactants to adsorb on condensates, affecting the activities of transcriptional condensates.

AB - The condensate-forming ability of transcription factors (TFs) has received considerable attention, although how condensates function in transcription remains unclear. In this issue of Developmental Cell, Wang et al. show that target DNA and transcriptional regulators work as soap-like surfactants to adsorb on condensates, affecting the activities of transcriptional condensates.

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U2 - 10.1016/j.devcel.2023.05.002

DO - 10.1016/j.devcel.2023.05.002

M3 - Comment/debate

C2 - 37279696

AN - SCOPUS:85160279444

SN - 1534-5807

VL - 58

SP - 915

EP - 916

JO - Developmental cell

JF - Developmental cell

IS - 11

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Soaping up transcriptional condensates

Abstract

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