Smelling Danger: Olfactory Stem Cells Control Immune Defense during Chronic Inflammation

Justin Rustenhoven; Jonathan Kipnis

doi:10.1016/j.stem.2019.09.006

Smelling Danger: Olfactory Stem Cells Control Immune Defense during Chronic Inflammation

Justin Rustenhoven, Jonathan Kipnis

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

Neurogenesis is critical to continuously replacie olfactory neurons but is impaired during chronic inflammatory rhinosinusitis. In this issue of Cell Stem Cell, Chen et al. (2019) describe the inflammation-induced switching of olfactory stem cells from a regenerative phenotype to one participating in immune defense; this process contributes to deficient replacement of olfactory sensory neurons.

Original language	English
Pages (from-to)	449-451
Number of pages	3
Journal	Cell Stem Cell
Volume	25
Issue number	4
DOIs	https://doi.org/10.1016/j.stem.2019.09.006
State	Published - Oct 3 2019

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title = "Smelling Danger: Olfactory Stem Cells Control Immune Defense during Chronic Inflammation",

abstract = "Neurogenesis is critical to continuously replacie olfactory neurons but is impaired during chronic inflammatory rhinosinusitis. In this issue of Cell Stem Cell, Chen et al. (2019) describe the inflammation-induced switching of olfactory stem cells from a regenerative phenotype to one participating in immune defense; this process contributes to deficient replacement of olfactory sensory neurons.",

author = "Justin Rustenhoven and Jonathan Kipnis",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = oct,

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doi = "10.1016/j.stem.2019.09.006",

language = "English",

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journal = "Cell Stem Cell",

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T1 - Smelling Danger

T2 - Olfactory Stem Cells Control Immune Defense during Chronic Inflammation

AU - Rustenhoven, Justin

AU - Kipnis, Jonathan

PY - 2019/10/3

Y1 - 2019/10/3

N2 - Neurogenesis is critical to continuously replacie olfactory neurons but is impaired during chronic inflammatory rhinosinusitis. In this issue of Cell Stem Cell, Chen et al. (2019) describe the inflammation-induced switching of olfactory stem cells from a regenerative phenotype to one participating in immune defense; this process contributes to deficient replacement of olfactory sensory neurons.

AB - Neurogenesis is critical to continuously replacie olfactory neurons but is impaired during chronic inflammatory rhinosinusitis. In this issue of Cell Stem Cell, Chen et al. (2019) describe the inflammation-induced switching of olfactory stem cells from a regenerative phenotype to one participating in immune defense; this process contributes to deficient replacement of olfactory sensory neurons.

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U2 - 10.1016/j.stem.2019.09.006

DO - 10.1016/j.stem.2019.09.006

M3 - Short survey

C2 - 31585089

AN - SCOPUS:85072328150

SN - 1934-5909

VL - 25

SP - 449

EP - 451

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 4

ER -

Smelling Danger: Olfactory Stem Cells Control Immune Defense during Chronic Inflammation

Abstract

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